![]() ![]() Mouro FM, Batalha VL, Ferreira DG, Coelho JE, Baqi Y, Müller CE, Lopes LV, Ribeiro JA, Sebastião AM (2017). Ex vivo model of epilepsy in organotypic slices-a new tool for drug screening. Magalhães DM, Pereira N, Rombo DM, Beltrão-Cavacas C, Sebastião AM, Valente CA (2018). Funding Agency: Fundação para a Ciência e a Tecnologia. Funding Agency: Fundação para a Ciência e a Tecnologia.Ģ018/2021 Controlo mecanistico e optogenético da astroglia para reparação neuronal. Funding Agency: Fundação para a Ciência e a Tecnologia.Ģ018/2021 Titanic- CYP46A1 as new Therapeutic Target in Niemann-Pick Type-C disease. Funding Agency: Fundação para a Ciência e a Tecnologia.Ģ018/2021 Regulação da homeostase e polarização pró-inflamatória da microglia Rac1. Coordinator: Coordinator: Ana M Sebastião. Funding Agency: Fundação para a Ciência e a Tecnologia.Ģ018/2021 Na procura do mecanismo de ação de um novo e seletivo fármaco antiepiléptico. Funding Agency: Fundação para a Ciência e a Tecnologia.Ģ018/2021 Astrossomas: Astrócitos Artificiais como reguladores da comunicação neuronal. Funding Agency: European Commission.Ģ018/2021 Restabelecimento dos níveis de Adenosina: nova abordagem para o tratamento da Sindrome de Rett. Ongoing Research Projects 2020/2023 Twinning - EpiEpiNet - Epileptogenesis and Epilepsy Network: from genes, synapses and circuits to pave the way for novel drugs and strategies. Control of post-natal neurogenesis and oligodendrogenesis. The group aims to understand how post-natal formation of new neurons and oligodendrocytes is regulated and its implications for the control of neuronal diseases as multiple sclerosis.Neurobiology of inflammation - interplay with epilepsy. This group aims to understand the relationship between inflammation and epilepsy to identify key points in the inflammatory cascade that may constitute as therapeutic targets to prevent epileptogenesis.The implications for developmental epilepsies, ageing and Alzheimer’s disease are under focus. ![]() ![]() Neurotrophic factors. This group aims to understand the causes and mechanisms of neuronal dysfunction caused by the lack of trophic support to synapse formation/ maturation/ protection.Motor neuron. This group aims to elucidate the fine tune control of motor neuron activity under normal and pathological conditions, as amyotrophic lateral sclerosis (ALS).Following this research line, the group evaluates the synaptic and behavioural (learning, memory, anxiety, depression) consequences of long term manipulation of endogenous modulator (adenosine and cannabinoids) signaling. Modulation of the tripartite synapse. This group aims to elucidate pre- post and glial mechanisms involved in the control of the delicate balance between neuronal inhibition and excitation and its implications for synaptic plasticity.The Unit is constituted by balanced multidisciplinary team organized in five groups according to their specific research topics, as follows: ![]()
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![]() ![]() Alice finds herself confused amongst the big changes occurring in the company. once a small volunteer group has now grown into a commercial enterprise. Being marked by the XGC herself, Alice does not hesitate to follow after Yūgo. She becomes anxious when Yūgo goes out alone to discover the origins of the 'XGC', a mark that appears on the bodies of Zoanthropes and bringing great power but at the cost of their life. In doing so, she leaves her job as a professional nurse. Concerned for his welfare, she chased after him.īeing a close friend with Yūgo, she decides to follow him to participate in the activities of the Non-Government Organization (NGO), the World of Co-Existence (W.O.C.). But as she tried to talk to him, he left the hospital. One day, her friend Yūgo was brought into the hospital where got tested on. Īfter graduating from high school, she became a nurse. After the events of the story, Alice is adopted by her aunt Mitsuko and lives a peaceful life as a part of her family. Because the girl sacrificed herself by distracting Alice's pursuers during her escape, Alice decided to come out of hiding and fight against the institution. While hiding herself to regain her composure, she began to worry about a girl that Alice befriended in the institution. However, she managed to escape the institution before being brainwashed, earning herself the freedom she had long sought. After being subjected to physical experimentation, her latent powers were awakened, after which she was used as a test subject and given battle training. In order to learn the truth, Yūgo sets out on a journey.Īlice Voiced by: Mika Kanai ( Bloody Roar, Bloody Roar II, Bloody Roar 3), Ruri Asano ( Bloody Roar Extreme onwards)Īlice Nonomura ( 野々村アリス, Nonomura Arisu ?) ( Alice Tsukagami ( 塚神アリス, Tsukagami Arisu ?) in Bloody Roar) is a rabbit zoanthrope who was kidnapped as a child by a secret research institution that conspired to use zoanthropes as weapons. He was sure she had been a victim during the incident with the XGC a year before and was still in a hospital somewhere. Also, that the name of this 'Black Shadow' was Nagi. While out investigating the incidents he heard rumors of a 'Black Shadow'. Yūgo has been racking his brains over the violence occurring. Yūgo accepts, wanting to learn more of the 'bad' activities going on behind the scenes. The man gives him an invitation to the tournament. Yūgo had worked out for himself who they were working for. Prior to his visit, a group of men and a woman had attacked Yūgo as part of a test to show the representative his legendary skills. He sets out to uncover the truth.Ī representative of the Zoanthrope tournament visits Yūgo. The 'XGC' will eventually end his life and end the lives of others who are afflicted if he doesn't find out how to stop it. But a mark known as the 'XGC' appears on his body. Their goal is to build a bright future for both humans and Zoanthropes alike. Yūgo becomes the leader of an NGO (Non-Government Organization) called the W.O.C. He assumes this is a sign that Tylon might be resurfacing and decides to fight back and rescue his younger brother. One day, five years after the incident with Tylon, Kenji is mysteriously abducted by a strange person. The boy had no memories and nobody to take care of him, so Yūgo took it upon himself to adopt him as his brother and named him Kenji. He is not truly alone, as he took under his wing a boy he found during the destruction of Tylon. Īfter the fall of Tylon, Yūgo hides his Zoanthropy and takes up a career as a boxer. Yūgo then promises his father that he will destroy their enemies with the powers that he inherited from him. Yūgo and Gadou eventually meet in a secret Tyron Corporation laboratory, where Gado reveals that Yūji was a zoanthrope who fought against the Tyron Corporation's mind control experiments and conversion process. Yūgo also seeks the mercenary Gado, the sole survivor of Yūji's combat unit. His father, Yūji Ōgami ( 大神勇二, Ōgami Yūji ?), was a mercenary said to have died in combat in a South American country. Yūgo Ōgami ( 大神勇吾, Ōgami Yūgo ?), the series' protagonist, is a young wolf zoanthrope on a quest to uncover the circumstances of his father's death. Introduced in Bloody Roar Yūgo Voiced by: Nobutoshi Canna ( Bloody Roar), Hideo Ishikawa ( Bloody Roar II, Bloody Roar 3, Bloody Roar Extreme), Akimitsu Takase ( Bloody Roar 4) 4 Introduced in Bloody Roar: Primal Fury. ![]() ![]() ![]() If you are not into high-energy felines, this one will make your dreams come true. On the contrary, he likes to simply lounge around, sleep, eat, and cuddle a bit. He is not one to run around, climb trees, fight with other felines, and all that stuff. If you know a thing or two about the animated cartoon character Garfield, you probably know that he is a chill cat. Whether you end up with a mackerel, a ticked, striped, or spotted ginger tabby, prepare to take endless shots of her and add all to your Insta feed. They add to the beauty of the cat in more ways than one. Some have lip lines with freckles or black dots that present in circle shapes. They come with an adorable pink little nose that screams ‘kiss me please”, cute eyes that assure you of their love and devotions, and the all-time-favorite ginger coat with tabby markings. These adorable creatures are prized for their remarkable beauty. Sure, all cat colors and patterns are beautiful but there’s something truly special about the ginger cat. In such a case, you have to be very close to the ginger cat to see the tabby markings. When mutation occurs, the markings will appear very faint. Many people don’t know this because some appear to have a solid color with others having tabby markings on them. The stats show that for every 5 ginger tabbies, you have only one being female.įun fact: All ginger cats are tabbies. To become a ginger tabby, a male cat only needs the gene from his mom which is very easy to occur.Ī female tabby, on the other hand, will require the gene from both parents making her tabby chances very low. See, a female has two X chromosomes while a male has both X and Y. ![]() It is for this very reason that many ginger tabbies are male. The ginger color in cats is carried on the gene of the X chromosome.īesides determining the gender of the cat, the gene also impacts the color and pattern of the coat. The most common breeds with this pattern and color include the following: Since the ginger tabby is not a breed but a coat color and pattern, it can be found in many cat breeds except those of Russian Blues and Siamese. The more the pigment, the deeper the color and vice versa. Typically, the pigment gives color ranging from red to cream. The same pigment is what gives some human beings red hair. ![]() The ginger coloring is a result of the pigment pheomelanin. If the dominant gene is ticked, the ticked tabby pattern will mask all the other patterns. The recessive gene affects the exact pattern the cat will have. There are four different patterns including the classic, mackerel, striped, and ticked. The pattern is the result of the agouti gene which causes the cat to have bands of heavy and light pigmentation on his body. Like other cat colors and patterns, the ginger tabby gets his markings and color from his genetic makeup. Where Does A Ginger Tabby Originate From? In this guide, we will go over the good and bad of owning a ginger tabby cat.īefore buying one, you might want to arm yourself with this information. On the other hand, they come with a few challenges of their own. They are affectionate, intelligent, a little mysterious, and playful. No wonder they are in almost every home you step your foot into. In addition to beauty, tabby cats have some of the best temperaments in the feline world. The tabby pattern combines with the ginger color to make an exceptionally beautiful cat. What a unique color and pattern choice for a feline friend! No doubt, this one is a showstopper! As an Amazon Associate, we may receive a small commission from qualifying purchases but at no extra cost to you. ![]() |